The prevalence of allergies seems to be increasing everyday. From annoying pollen and cat allergies to deadly peanut allergies and very dangerous asthma. They all results from our bodies overreacting to what should be a benign substance.
A way to stop our bodies from reacting to non-threatenings substances is the focus of this new research. The essence of this is to force our bodies to accept these specific allergy agents as harmless and not harmful.
Thus for, the science has focused on suppressing the reaction within the body to lessen the impact of your body’s reaction to the foreign substance. This new method forces the body to accept these allergens as benign.
Using nanoparticles to get the allergens past the initial immune system response.
While it has only been tested in mice to this point the research looks very promising and is progressing to clinical trials as a treatment for all allergies.
“It’s a universal treatment,” said lead researcher Stephen Miller from Northwestern University in Chicago. “Depending on what allergy you want to eliminate, you can load up the nanoparticle with ragweed pollen or a peanut protein.”
“The findings represent a novel, safe and effective long-term way to treat and potentially ‘cure’ patients with life-threatening respiratory and food allergies,” he added. “This may eliminate the need for life-long use of medications to treat lung allergy.”
To get the body to recognize the allergen as an acceptable and non-threatening to our immune system, we need to smuggle these substances past the initial immune system.
To get past this, they developed dissolvable nanoparticles from an FDA-approved polymer. By housing the allergen inside of the polymer, it gets passed the initial immune response and is then consumed by macrophages which gives your body the signal that the allergen is not a threatening intruder.
“The vacuum-cleaner cell presents the allergen or antigen to the immune system in a way that says, ‘No worries, this belongs here,'” said Miller. The immune system then shuts down its attack on that allergen, and gets reset to normal.